Vantrel McMillan played his college ball at the University of Tennessee-Chattanooga, where he was a teammate of quarterback Alejandro Bennifield. After redshirting in 2012, and missing his freshman season due to injury, McMillan first appeared for the Mocs in 2014. The Albany, Georgia native appeared in 10 games totaling 16 tackles, 2 sacks, and 5.5 tackles for loss, which earned him more playing time in his junior season in 2015. The 6’3 260 pound defensive lineman progressed in his Junior season, finishing with 42 tackles, 6.5 tackles for loss, 2 forced fumbles, 1 interception, and 1.5 sacks. 2016 was McMillan’s best season as a Moc, as he finished with 57 tackles, 7.5 sacks, and 14 tackles for loss, earning First Team All-Southern Conference honors.
Following his breakout senior season, McMillan received an invitation to the Seattle Seahawks mini camp, but fell short of making the team’s roster. In 2018, McMillan played for the Montreal Alouettes, appearing in 4 games, totaling 1 sack, 4 tackles, 1 tackle for a loss, and one fumble recovery. McMillan then went on to sign with the XFL’s Houston Roughnecks, where he appeared in 4 games, before the league’s season was cut short due to the COVID-19 Pandemic.
Vantrel McMillian signed with the Pirates right before their playoff run in 2021. He appeared in the Pirates 44-19 victory over the Bismarck Bucks in the opening round of the IFL playoffs. His play helped Massachusetts to earn its first ever playoff win as McMillan recorded five tackles including one for a loss, he also broke up a pass. McMillan will be back for the Pirates in 2022, fresh off the United Bowl win. This will be his age-28 season.